Sampling for PFAS must be conducted with extreme care due to its persistence in the environment. In California, laboratory staff undergo extensive training to follow strict protocols to avoid false positives. Factors such as recent gasoline handling, new clothing, and personal care products like makeup and deodorant must be avoided while conducting PFAS testing. Quality control measures, including field reagent blanks, help distinguish between true environmental contamination and external interference. These protocols ensure accurate detection, as PFAS levels are extremely low.